Unexplained infertility is not the end of the road. Despite its definite-sounding name, there are ways to combat unexplained fertility. In fact, many couples are able to have children after a diagnosis.
I’m a 24-year-old, and I’ve always had extremely painful periods. My doctor told me that I might have endometriosis. What is it, and what can be done about it?
Endometriosis is defined by having cells and tissue normally confined to the uterus (the endometrium) elsewhere in the body, usually within the pelvis and abdomen. During a period, the endometrium is shed each month as menstrual flow. Unfortunately, when this tissue is elsewhere, it does not get shed – but can cause inflammation and scarring.
A few theories exist; one is “retrograde menstruation”–endometrium that backs up the fallopian tubes during a period. Another is a change from the normal cells that line the abdominal cavity to endometrial cells–a process called metaplasia. In any case, when looked at under the microscope, endometriosis appears just like normal endometrial tissue.
For many, it means very painful menstrual periods refractory to over-the-counter medications. Endometriosis responds to hormones much like normal endometrium, and this can cause cramping and pain. Sometimes this results in chronic inflammation leading to pelvic pain outside of periods and painful intercourse. Occasionally, endometriosis is not painful, but still causes scarring of the ovaries and fallopian tubes and infertility.
Health providers often presumptively diagnose endometriosis on the basis of symptoms and physical exam. Laparoscopy (introducing a camera within the abdomen) with biopsy confirms the diagnosis. Since endometriosis responds to hormones, treatment is often directed there. Birth control pills, Depo-Provera, and Depo-Lupron (a medication that shuts off ovarian hormone production) are all commonly used. Endometriosis can also be ablated directly using the laparoscope and cautery or laser. Occasionally it is severe enough that hysterectomy is required.
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